Yeast-based fermentation processes can have several problems, such as low production rates, titers or yields; product/substrate toxicity or strain instability.

We can improve existing yeast strains for established or pilot processes using a variety of synthetic biology tools for fast strain improvement and screening.

Creating new production strains involves testing new pathways, screening for new genes from different organisms, and rewiring of yeast metabolic networks.

With knowledge and expertise in a variety of different metabolic pathways, we can initially develop proof-of-concept yeast strains for your desired product. This allows you to de-risk a project by a quick assessment of production potential for your target product. Further on, we can screen through multiple iterations for improvements of these strains towards a stage where these are ready for scale up.

Improvement and creation of microbial production strains requires straightforward measurements of either the end product or an intermediary.

We can develop synthetic biology tools for screening and improvement of microbial cell factories. Prime examples of this are biosensors for key metabolites that can be used to select high producer cells and screen multiple genetic targets.